Up is def one of my favorite Pixar movies, it's the only one that had me crying within 30 minutes. Up's cute and amazing story takes you through the entire range of human emotions and is just a thrilling ride.
This is an amazing comedy, with about three points that will make *anyone* cry. The intro is a case study in masterful storytelling. But I must emphasize the warning. I'm not someone who cries at movies. This was an exception.