Palo Alto, CA, USA
For a story so intricately tied to the main character's mental state, it's remarkable how much time is spent on mindless action sequences. It's the worst sort of negative spiral: There's so much action that you don't have time to connect with the characters, and because you don't care about the characters the action becomes boring.
This could have been an amazing movie.
Think of everything you've ever heard of about Dr. Frankenstein's monster - that moaning, groaning, imbecilic abomination. Now throw all of that out the window, because the original novel is so startlingly different (and surprisingly good!) that it may as well be completely unrelated.